MYCOCIDE PRO
4% Chlorhexidine Gluconate Scrub

Indications:

MYCOCIDE PRO is a versatile antimicrobial scrub, ideal for use in veterinary clinics, hospitals, pet grooming salons, and pet boarding facilities. It is recommended for:

• Pre-surgical hand scrubbing
• Skin antisepsis before surgery
• Cleaning and disinfecting wounds
• General cleaning and sanitization
• Hand washing and scrubbing for healthcare staff

How MYCOCIDE PRO Works:

MYCOCIDE PRO's active ingredient, Chlorhexidine, is a powerful broad-spectrum biocide that targets a wide range of microorganisms, including Gram-positive and Gram-negative bacteria, as well as fungi. It acts faster and covers a broader spectrum compared to other antimicrobials like antibiotics. Chlorhexidine can either inhibit bacterial growth (bacteriostatic) or kill bacteria outright (bactericidal) depending on its concentration, by disrupting the cell membrane.

• Bacterial Action: Chlorhexidine binds quickly to bacterial cell walls, causing rapid disruption. This destabilization allows Chlorhexidine to penetrate the cell, attacking the cytoplasmic membrane and ultimately causing cell death. At higher concentrations, it solidifies the cell contents, leading to rapid bacterial death.
• Fungal Action: Chlorhexidine acts similarly on fungi, quickly breaching the cell wall and membrane, leading to the leakage of vital cellular components and cell death.
• Biofilm Inhibition: Chlorhexidine helps prevent the formation and adherence of biofilms, protective layers formed by microbial communities. This reduces the risk of persistent infections.

Additional Microbial Protection: Chlorhexidine also demonstrates activity against a variety of other microorganisms, including bacterial spores, protozoa, and certain enveloped viruses such as herpes simplex, HIV, and influenza. Its broad spectrum of action reduces the chances of opportunistic infections.

Chlorhexidine in Healthcare: Prolonged Protection

In topical applications, Chlorhexidine binds to proteins in the skin and mucous membranes, providing long-lasting antimicrobial protection through slow release—a property known as substantivity. This ensures continued effectiveness for at least 48 hours. Unlike other agents, such as povidone-iodine, Chlorhexidine remains effective even in the presence of body fluids like blood.

In dental care, Chlorhexidine adheres to oral tissues and teeth, offering sustained antimicrobial action that helps reduce bacterial count and prevent dental plaque. It is also used in medical devices like catheters and dressings to prevent microbial colonization and biofilm formation, providing added protection in healthcare settings.

Advantages of Skin Cleansing with MYCOCIDE PRO CHG 4%

• Persistent Reduction in Microbial Density: CHG skin cleansing significantly reduces microbial skin colonization, lowering infection risks by several log factors. For instance, a 1-log reduction equates to a 90% decrease in bacteria.
• Daily Use and Baseline Reduction: Daily CHG bathing helps maintain consistently low levels of bacterial presence on the skin. This minimizes deficiencies in skin antisepsis and reduces cross-contamination in healthcare environments.
• Residual Antimicrobial Effect: CHG leaves a residual effect on the skin that continues to protect against colonization and infection after application, maintaining low microbial levels over time and further reducing infection risk.
• Undiluted Application: Studies show that applying undiluted CHG directly to the skin is essential for effective bacterial reduction. Diluting CHG has been associated with a higher bacterial load remaining on the skin, compromising its efficacy.

Efficacy:

• Fast-Acting: Begins killing bacteria and fungi within 30 seconds of application.
• Long-Lasting: Provides antimicrobial protection for up to 6 hours after use.

Recommendations for Use:

1. Pre-Surgical Hand Scrubbing:
   • Wet hands and forearms with water.
   • Apply about 5 mL of MYCOCIDE PRO and scrub thoroughly for 3 minutes.
   • Rinse and repeat if necessary.
2. Skin Antisepsis:
   • Apply directly to the surgical site.
   • Scrub for at least 2 minutes.
   • Rinse with sterile water or saline.
3. Wound Cleaning:
   • Dilute 1 part MYCOCIDE PRO with 1 part water.
   • Apply to the wound.
   • Gently scrub and rinse with water.
4. General Cleaning and Sanitization:
   • Dilute 1 part MYCOCIDE PRO with 10 parts water for high-traffic and infectious areas.
   • Dilute 1 part to 20 parts water for moderate, low, and non-infectious traffic areas.
   • Use to clean surfaces, equipment, and areas in the clinic, grooming areas, or salon.

Uses of MYCOCIDE PRO CHG 4% in Various Settings:

Pet Shops:

• Grooming Products: Chlorhexidine is used in antibacterial shampoos and scrubs to control skin infections, treat hotspots, and reduce odors caused by bacterial and fungal growth.
• Ear Cleaners: It is included in ear-cleaning solutions to prevent and treat ear infections.
• Wound Care: Chlorhexidine is applied to minor cuts, abrasions, and wounds on pets to prevent infections and promote faster healing.
• Sanitization: Used to disinfect cages, grooming tools, and other equipment, maintaining a hygienic environment.

Veterinary Clinics:

• Surgical Prep: Used for pre-surgical hand scrubbing and to prepare the surgical site, reducing the risk of post-surgical infections.
• Wound Management: Applied to clean and disinfect wounds, surgical incisions, and abscesses.
• Oral Care: Used in mouthwashes and rinses to reduce bacterial load and prevent periodontal disease.
• General Disinfection: Applied to examination tables, surgical instruments, and other surfaces to prevent the spread of pathogens.
• Antiseptic Bandages: Chlorhexidine-impregnated dressings provide continuous antimicrobial action.

Poultry Supplies:

• Water Sanitization: Added to drinking water in animal selling / housing site to control microbial load and prevent the spread of diseases.
• Surface Disinfection: Used to disinfect surfaces in poultry houses, feeders, and waterers.
• Footbaths: Used in footbaths at the entrances as a biosecurity measure.
• Wound Treatment: Applied to treat and prevent infections in wounds or cuts on animals.

These diverse uses of MYCOCIDE PRO CHG 4% highlight its critical role in maintaining hygiene, preventing infections, and ensuring the health of animals across different environments.

Safety and Precautions:

• For external use only.
• Avoid contact with eyes and mucous membranes.
• Discontinue use if irritation occurs and consult a veterinarian.
• Keep out of reach of children.